AD/PD 2021 Presentations

Characterization of genetic and environmental influences in a novel mouse model of late-onset AD  Adrian L. Oblak Effects of Western Diet in Modeling Late-Onset Alzheimer’s Disease in Laboratory Mice   Kevin Kotredes  Kotredes P334 ADPD 2021 Diet Determining...

AAIC 2021 Posters

The synergistic role of high-fat diet and genetic predisposition in Alzheimer’s disease. Adrian L. Oblak, Kevin Kotredes, Ravi Pandey, Mike Sasner, Greg Carter, Bruce Lamb and Gareth Howell. Poster #55514, IP-BSP-1 [In-Person Posters] Basic Science & Pathogenesis:...

AD Knowledge Portal Data Release 17.5

The Jax.IU.Pitt_Rat_TgF344-AD Study This is a study of a familial Alzheimer’s disease transgenic rat model expressing human APP with the Swedish mutation (KM670/671NL) and human PSEN1 with the Δ exon 9 mutation. Previously released was beta amyloid and proinflammatory...

Molecular estimation of neurodegeneration pseudotime in older brains

Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A Garden, Anna K Greenwood, Solveig K Sieberts, Philip L De Jager, Nilüfer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, Benjamin A Logsdon. Molecular estimation of neurodegeneration pseudotime...

MODEL-AD Publications June-July 2020

Sukoff Rizzo SJ, Masters A, Onos KD, Quinney S, Sasner M, Oblak A, Lamb BT, Territo PR; MODEL‐AD consortium. Improving preclinical to clinical translation in Alzheimer's disease research. Alzheimers Dement (N Y). 2020 Jun 14;6(1):e12038. doi: 10.1002/trc2.12038....

MODEL-AD Presentations at AAIC 2020

Featured Research Sessions Monday, July 27, 2020: 8:30 AM - 9:30 AM    Microbiome in Alzheimer’s Disease: Pathogenesis and Treatment Implications  [SFRS1-02 Virtual Room Name: The Hague]  Speakers: Dr. Meiyu Geng, Sam Sisodia, Michael Heneka, Bruce...