AD/PD 2021 Presentations
Characterization of genetic and environmental influences in a novel mouse model of late-onset AD Adrian L. Oblak Effects of Western Diet in Modeling Late-Onset Alzheimer’s Disease in Laboratory Mice Kevin Kotredes Kotredes P334 ADPD 2021 Diet Determining...
AAIC 2021 Posters
The synergistic role of high-fat diet and genetic predisposition in Alzheimer’s disease. Adrian L. Oblak, Kevin Kotredes, Ravi Pandey, Mike Sasner, Greg Carter, Bruce Lamb and Gareth Howell. Poster #55514, IP-BSP-1 [In-Person Posters] Basic Science & Pathogenesis:...
AD Knowledge Portal Data Release 17.5
The Jax.IU.Pitt_Rat_TgF344-AD Study This is a study of a familial Alzheimer’s disease transgenic rat model expressing human APP with the Swedish mutation (KM670/671NL) and human PSEN1 with the Δ exon 9 mutation. Previously released was beta amyloid and proinflammatory...
A novel systems biology approach to evaluate mouse models of late-onset Alzheimer’s disease
Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P Kotredes, Harriet Williams, Lara M Mangravite, Bruce T Lamb, Adrian L Oblak, Gareth R Howell, Michael Sasner, Benjamin A Logsdon, MODEL-AD...
Molecular estimation of neurodegeneration pseudotime in older brains
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A Garden, Anna K Greenwood, Solveig K Sieberts, Philip L De Jager, Nilüfer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, Benjamin A Logsdon. Molecular estimation of neurodegeneration pseudotime...
Model organism development and evaluation for late-onset Alzheimer’s disease: MODEL-AD
Adrian L Oblak, Stefania Forner, Paul R Territo, Michael Sasner, Gregory W Carter, Gareth R Howell, Stacey J Sukoff-Rizzo, Benjamin A Logsdon, Lara M Mangravite, Ali Mortazavi, David Baglietto-Vargas, Kim N Green, Grant R MacGregor, Marcelo A Wood, Andrea J...
MODEL-AD Publications June-July 2020
Sukoff Rizzo SJ, Masters A, Onos KD, Quinney S, Sasner M, Oblak A, Lamb BT, Territo PR; MODEL‐AD consortium. Improving preclinical to clinical translation in Alzheimer's disease research. Alzheimers Dement (N Y). 2020 Jun 14;6(1):e12038. doi: 10.1002/trc2.12038....
MODEL-AD Presentations at AAIC 2020
Featured Research Sessions Monday, July 27, 2020: 8:30 AM - 9:30 AM Microbiome in Alzheimer’s Disease: Pathogenesis and Treatment Implications [SFRS1-02 Virtual Room Name: The Hague] Speakers: Dr. Meiyu Geng, Sam Sisodia, Michael Heneka, Bruce...