by abbottmj | Jan 12, 2021 | Uncategorized
The Jax.IU.Pitt_Rat_TgF344-AD Study This is a study of a familial Alzheimer’s disease transgenic rat model expressing human APP with the Swedish mutation (KM670/671NL) and human PSEN1 with the Δ exon 9 mutation. Previously released was beta amyloid and proinflammatory...
by abbottmj | Dec 21, 2020 | Uncategorized
Christoph Preuss, Ravi Pandey, Erin Piazza, Alexander Fine, Asli Uyar, Thanneer Perumal, Dylan Garceau, Kevin P Kotredes, Harriet Williams, Lara M Mangravite, Bruce T Lamb, Adrian L Oblak, Gareth R Howell, Michael Sasner, Benjamin A Logsdon, MODEL-AD...
by abbottmj | Dec 21, 2020 | Uncategorized
Sumit Mukherjee, Laura Heath, Christoph Preuss, Suman Jayadev, Gwenn A Garden, Anna K Greenwood, Solveig K Sieberts, Philip L De Jager, Nilüfer Ertekin-Taner, Gregory W Carter, Lara M Mangravite, Benjamin A Logsdon. Molecular estimation of neurodegeneration pseudotime...
by abbottmj | Dec 21, 2020 | Uncategorized
Adrian L Oblak, Stefania Forner, Paul R Territo, Michael Sasner, Gregory W Carter, Gareth R Howell, Stacey J Sukoff-Rizzo, Benjamin A Logsdon, Lara M Mangravite, Ali Mortazavi, David Baglietto-Vargas, Kim N Green, Grant R MacGregor, Marcelo A Wood, Andrea J...
by abbottmj | Jul 21, 2020 | Uncategorized
Sukoff Rizzo SJ, Masters A, Onos KD, Quinney S, Sasner M, Oblak A, Lamb BT, Territo PR; MODEL‐AD consortium. Improving preclinical to clinical translation in Alzheimer’s disease research. Alzheimers Dement (N Y). 2020 Jun 14;6(1):e12038. doi: 10.1002/trc2.12038....
by abbottmj | Jul 6, 2020 | Uncategorized
Featured Research Sessions Monday, July 27, 2020: 8:30 AM – 9:30 AM Microbiome in Alzheimer’s Disease: Pathogenesis and Treatment Implications [SFRS1-02 Virtual Room Name: The Hague] Speakers: Dr. Meiyu Geng, Sam Sisodia, Michael Heneka, Bruce...
by abbottmj | Jun 4, 2020 | Uncategorized
Milind N, Preuss C, Haber A, Ananda G, Mukherjee S, John C, Shapley S, Logsdon BA, Crane PK, Carter GW. PLoS Genet. 2020 Jun 3;16(6):e1008775. doi: 10.1371/journal.pgen.1008775. [Epub ahead of print] PMID: 32492070 [PubMed – as supplied by publisher]...
by abbottmj | Jan 8, 2020 | Uncategorized
Pandey RS, Graham L, Uyar A, Preuss C, Howell GR, Carter GW. https://www.ncbi.nlm.nih.gov/pubmed/31878951
by tjackson | Nov 1, 2019 | Uncategorized
The Preclinical Testing Core (PTC) of the MODEL-AD) consortium supports preclinical screening of test compounds nominated by the greater research community. The PTC has established a streamlined preclinical drug testing strategy with go/no-go decision points that...
by tjackson | Sep 5, 2019 | Uncategorized
Monday, October 21, 2019 Session #354 – 4:15-4:30 PM – McCormick Place: Room S103 Title: Developing mouse models to study late-onset Alzheimer’s Disease D. BAGLIETTO-VARGAS1,2, L. CAI1, M. NGUYEN1, K. HUYNH1, A.C. MARTINI1, L. TRUJILLO-ESTRADA1, C. SOTO3, I....
