| Invitation Format | Poster # & Date/Time | Session Title | Presentation Title |
| Poster | Poster #66288
Saturday, July 30, 2022: 12:25 PM – 1:40 PM MT, San Diego Convention Center, Exhibit Hall — DEF |
[Poster: Alzheimer’s Imaging Consortium] Neuroimaging and preclinical diagnosis | Differential vulnerability of hippocampal microstructure in 5xFAD mouse model of Alzheimer’s Disease: A dMRI study |
| Poster | Poster #63682
Sunday, July 31, 2022 |
P1-03 [In-Person Posters Sun] Basic Science and Pathogenesis: Genetics | Cerebral perfusion and glucose metabolism profiling reveal special phenotypes in the hAPOE3, hAPOE4, Trem2 risk, and doubled risks mice |
| Poster | Poster #66966
Sunday, July 31, 2022 |
P1-00 [In-Person Posters Sun] Student Poster Competition | Impact of Phospholipase C Gamma 2 Alzheimer’s Disease Variants on Microglial Biology and Disease Pathogenesis |
| Poster | Poster #64485
Sunday, July 31, 2022: 7:00 AM – 11:55 PM MT, Virtual Platform |
Virtual Only Posters | A novel, humanized late-onset Alzheimer’s disease mouse model expressing APOEe4, Trem2*R47H, and amyloid-beta. |
| Poster | Poster #65160
Sunday, July 31, 2022: 7:00 AM – 11:55 PM MT, Virtual Platform |
Virtual Only Posters | The niacin receptor HCAR2 induces a protective response of microglia to amyloid pathology. |
| Poster | Poster #65967
Sunday, July 31, 2022: 7:00 AM – 11:55 PM MT, Virtual Platform |
Virtual Only Posters | Application of neurovascular uncoupling and whole brain network connectomics to assess the role of genetic and dietary risk factors in the LOAD2 mouse model. |
| Poster | Poster #64303
Sunday, July 31, 2022: 9:15AM-4:45 PM MT, San Diego Convention Center, Exhibit Hall DEF |
P1-07 [In-Person Posters Sun] Biomarkers: Neuroimaging | A novel whole-brain imaging pipeline for high resolution spatial and temporal measurements of amyloid-beta plaque dynamics in pre-clinical Alzheimer’s Disease animal models |
| Poster | Poster #65930
Sunday, July 31, 2022 |
Basic Science and Pathogenesis: Molecular and Cell Biology | ABCA7*V1599M variant in 5xFAD mice mediates differences in amyloid-beta pathology and reactive gliosis |
| Poster | Poster #63718
Sunday, July 31 |
Postdoctoral Poster Competition | Late-onset AD risk mutation PICALMH458R prevents plaque generation in 5xFAD mice |
| Poster | Poster #66994
Sunday, July 31, 2022 |
Biomarkers: biomarkers (non-neuroimaging) | Plasma metabolomic signatures of lipid and cellular energy metabolism in the 5xFAD mouse |
| Poster | Poster #63702
Monday, August 1, 2022 |
P2-05 [In-Person Posters Mon] Basic Science and Pathogenesis: Molecular and Cell Biology | INPP5D inhibition attenuates amyloid pathology through the regulation of microglial functions. |
| Poster | Poster #66024
Monday, August 1, 2022 |
P2-05 [In-Person Posters Mon] Basic Science and Pathogenesis: Molecular and Cell Biology | Cx3cr1 deficiency aggravates Aβ driven neurodegeneration and cognitive decline in a mouse model of Alzheimer’s disease. |
| Poster | Poster #67648
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | Comparative characterization of 5XFAD and hAbetaSAA mouse models of familial AD |
| Poster | Poster #64175
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | Deciphering the genetic interaction between klotho and APOE with novel mouse models |
| Talk | Monday, August 1, 2022, 2:15-3:30 p.m. | Virtual Session #66802: Glial Biomarkers in Alzheimer’s Disease. | Longitudinal changes in brain glucose metabolism, astrocyte biomarkers and behavior in an APP/PS1 rat model |
| Poster | Poster #66218
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | BIN1 K358R variant in 5xFAD mice ameliorates AB pathology and microgliosis. |
| Poster | Poster #66214
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | The Clu-rs2279590_h2kb variant suppresses the astrocytic response to plaques and reduces plasma Nfl in 5xFAD mice |
| Poster | Poster #62610
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | Trem2R47H NSS; 5xFAD mice display age/disease progression-dependent changes in plaques and plaque-associated microglia, and increased plasma neurofilament light chain |
| Poster | Poster #65285
Monday, August 1, 2022 |
P2-03 [In-Person Posters Mon] Basic Science and Pathogenesis: Genetics | Spatiotemporal transcriptomic characterization of an amyloid mouse model of Alzheimer’s disease |
| Poster | Poster #64137
Tuesday, August 2, 2022 |
P3-03 [In-Person Posters Tue] Basic Science and Pathogenesis: Genetics | Metabolomics Profiling Reveals Distinct Signatures in the Serum and Brain Metabolomes in Mouse Models of Alzheimer’s Disease |
| Poster | Poster #64606
Tuesday, August 2, 2022 |
P3-03 [In-Person Posters Tue] Basic Science and Pathogenesis: Genetics | Pharmacodynamics Assessment of Aducanumab in 5XFAD mice: A MODEL-AD PTC Study |
| Poster | Poster #67173
Tuesday, August 2, 2022 |
P3-03 [In-Person Posters Tue] Basic Science and Pathogenesis: Genetics | A clinically relevant mouse model of the Trem2*R47H Alzheimer’s disease risk variant |
| Poster | Poster #68781
Tuesday, August 2, 2022 |
P3-17 [Posters Tue Developing Topics] Drug Development: Nonhuman | A Target Enablement Package for the Inhibition of SHIP1 as a Therapeutic Strategy for the Treatment of Alzheimer’s Disease |
| Poster | Poster #66349
Tuesday, August 2, 2022 |
Basic Science and Pathogenesis: Genetics | Bulk and single-cell gene expression network analysis in mouse models of AD using PyWGCNA |
| Poster | Poster #68069
Wednesday, August 3, 2022 |
P4-03 [In-Person Posters Wed] Basic Science and Pathogenesis: Genetics | A more natural context: Variation in mouse background improves models of vascular contributions to Alzheimer’s Disease |
| Poster | Poster #68076
Wednesday, August 3, 2022 |
P4-03 [In-Person Posters Wed] Basic Science and Pathogenesis: Genetics | Genetically diverse mouse models of Alzheimer’s Disease reveal an association between amyloid deposition and glycan metabolism in the brain |
| Poster | Poster #66273
Wednesday, August 3, 2022 |
P4-03 [In-Person Posters Wed] Basic Science and Pathogenesis: Genetics | Phenotypic characterization of UCI MODEL-AD mice using RNA-seq |
| Poster | Poster #67665
Wednesday, August 3, 2022 |
P4-03 [In-Person Posters Wed] Basic Science and Pathogenesis: Genetics | The role of Abca7 in late-onset Alzheimer’s disease animal models |
