Wednesday, March 27th, 08:00-18:00, Exhibition Session Code A7.a

DEEP PHENOTYPING OF THE 5XFAD MOUSE MODEL USING THE MODEL-AD PIPELINE   ADPD 5xFAD poster AO
A. Oblak, H. Williams, G. Carter, S. Sukoff-Rizzo, M. Sasner, P. Territo, G. Howell, B. Lamb.
Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University School of Medicine, Radiology & Imaging Sciences, Indianapolis, USA.

MODELS OF LATE ONSET ALZHEIMER’S DISEASE: THE MODEL-AD CONSORTIUM  ADPD MODEL-AD overview poster AO
A. Oblak, G. Carter, G. Howell, S. Sukoff-Rizzo, M. Sasner, P. Territo, H. Williams, B. Lamb, A. Mortazavi, M. Wood, S. Forner, G. MacGregor, A. Tenner, K. Green, F. LaFerla.
Indiana University School of Medicine, Stark Neurosciences Research institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
University of California Irvine, MODEL-AD, Irvine, USA.

TREM2R47H MICE SHOW A TWO-FOLD REDUCTION IN EXPRESSION AND PROTEIN LEVELS OF TREM2  ADPD Trem2R47H poster AO
A. Oblak, R. Pandey, G. Carter, H. Williams, G. Howell, M. Sasner, B. Lamb.
Indiana University School of Medicine, Stark Neurosciences Research Institute, Indianapolis, USA.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.

EVALUATION OF CHRONIC TREATMENT WITH LEVETIRACETAM ON PHARMACOKINETCS AND PHARMACODYNAMICS IN 5XFAD MICE
S. Rizzo, S. Quinney, K. Onos, K. Keezer, L. Haynes, D. Jones, A. Masters, C. Biesdorf De Almeida, J. Meyer, J. Peters, S. Persohn, A. Bedwell, D. McKinzie, M. Sasner, G. Howell, H. Williams, A. Oblak, B. Lamb, P. Territo.
The Jackson Laboratory, Center for Biometric Analysis, Bar Harbor, USA.
Indiana University, School of Medicine, Indianapolis, USA.
The Jackson Laboratory, Institute for Mammalian Genomics, Bar Harbor, USA.

NOVEL MOUSE MODELS OF LATE-ONSET ALZHEIMER’S DISEASE EXPRESSING RISK VARIANTS AT GWAS LOCI    ADPD GWAS models poster MS
M. Sasner, A. Oblak, H. Williams, C. Preuss, G. Carter, G. Howell, B. Lamb.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University, Stark Neurosciences Research Institute, Indianapolis, USA.

CHARACTERIZATION OF A NOVEL MOUSE MODEL EXPRESSING APOE4 AND TREM2*R47h FOR FURTHERING THE UNDERSTANDING OF LATE ONSET ALZHEIMER’S DISEASE    ADPD APOE4-Trem2 poster MS
M. Sasner, A. Oblak, H. Williams, S. Rizzo, P. Territo, G. Howell, B. Lamb.
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA.
Indiana University, Stark Neurosciences Research Institute, Indianapolis, USA.

CHARACTERIZATION OF MOUSE MODELS BASED ON CANDIDATE GENES ASSOCIATED WITH LATE ONSET ALZHEIMER’S DISEASE   ADPD transcriptomics poster RP
R. Pandey
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA

Thursday, March 28th, 17:20 – 19:20, Auditorium VIII, Session code:S28

DEVELOPING THE NEXT GENERATION OF ANIMAL MODELS OF LATE-ONSET ALZHEIMER’S DISEASE
F. Laferla
University of California Irvine, School of Biological Sciences, Irvine, USA.

HUMAN WILD-TYPE ABETA KNOCK-IN MICE AS A BASIS TO STUDY SPORADIC ALZHEIMER’S DISEASE
D. Baglietto-Vargas, L. Cai, A. Martini, L. Trujillo-Estrada, S. Forner, S. Jiang, E. Kramár, C. Nuñez-Diaz, M. Shahnawaz, M. Dina, X. Ma, C. Da Cunha, R. Ager, C. Soto, A. Gutierrez, I. Moreno-Gonzalez, G. MacGregor, K. Green, M. Wood, A. Mortazavi, A. Tenner, F. LaFerla.
University of California- Irvine, Institute for Memory Impairments and Neurological Disorders, Irvine, USA.
University of California- Irvine, Department of Developmental and Cell Biology, Irvine, USA.
University of Malaga, Department of Cell Biology- Genetic and Physiology- Faculty of Sciences- Biomedical Research Institute of Malaga IBIMA- Networking Research Center on Neurodegenerative Diseases CIBERNED, Malaga, Spain.
University of Texas Health Science Center at Houston, The Mitchell Center for Alzheimer’s Disease and Related Brain Disorders- Department of Neurology- McGovern Medical School, Houston, USA.

Friday, March 29th, 17:15 – 19:15, Auditorium VI+VII

NEXT-GENERATION MOUSE MODELS OF ALZHEIMER’S DISEASE
G. Carter
The Jackson Laboratory, MODEL-AD, Bar Harbor, USA

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