Logsdon et al have used data from the AMP-AD consortium to identify consensus gene clusters that are differentially expressed in Alzheimer’s disease.
The MODEL-AD consortium has worked with nanoString to develop a transcriptomics panel to assay these modules in mouse models.
We expect that this will be a rapid, cost-effective and highly reproducible approach to assess clinical relevance of novel models, to monitor disease progression, and to assay potential therapeutics. The transcriptomics panel is now available from nanoString.