Monday, November 5, 1:30pm – 4pm
Session 345: Global Efforts to Build More Predictive Animal Models of Neurodegenerative Disease
Chair: Bruce T. Lamb, PhD, Indiana University School of Medicine
Co-Chair: Rudolph E. Tanzi, PhD, Massachusetts General Hospital, Harvard Medical School
Location: SDCC 6B 2:45-3:20PM
345.04 Bruce Lamb: Novel insights into Alzheimer’s disease through the MODEL-AD consortium

Nanosymposium 267: Alzheimer’s Disease: Neuroinflammation and Immune Actions
Location: SDCC 24
10:15-10:30 267.10 Kristen Onos: Genetic diversity is a significant driver of amyloid-induced neuroinflammation and neurodegeneration in APP/PS1 mice

Tuesday November 6
Poster Session 466: Alzheimer’s Disease and Other Dementias: Genetic Analysis and Omics Approaches
Systems biology-based method to identify and prioritize Alzheimer’s disease candidate driver genes
S. Mukherjee, T. M. Perumal, K. Daily, S. Sieberts, L. Omberg, C. Preuss, G. Carter, L. Mangravite, B. Logsdon
Board F23, #462.20 presented 11:00-12:00am

Poster Session 467: Alzheimer’s Disease and Other Dementias: Therapeutic Strategies: Preclinical Animal Models II
Novel models of late-onset Alzheimer’s disease
Mike Sasner for the MODEL-AD Center   Sasner SfN 2018 GWAS poster final
Board G8, #467.01 presented 8:00-9:00am

hAb-KI: A knock-in mouse model for sporadic Alzheimer’s disease
Stefania Forner for the MODEL-AD Center
Board G9, #467.02, presented 9:00-10:00am

MODEL-AD: Late-onset Alzheimer’s disease models
Adrian Oblak for the MODEL-AD Center   Oblak OverviewFINAL
Board G10, #467.03 presented 10:00-11:00am

Preclinical screening strategy of the MODEL-AD consortium: Evaluation of the pharmacokinetics and pharmacodynamics of treatment with Levetiracetam
Stacey Rizzo for the MODEL-AD Center   Rizzo et al SfN PTC MODELAD Poster – 20181029 vPRT_sjsr_FINAL
Board G11, #467.04 presented 11:00am-noon

Translational genetic and genomic analyses of new mouse models of Alzheimer’s disease
Greg Carter for the MODEL-AD Center   Carter_SFN_2018
Board G12, #467.05 presented 8:00-9:00am

MODEL-AD: Standardized characterization of familial Alzheimer’s disease models (5xFAD, 3Tg-AD, APP/PS1, and hTau)
Gareth Howell for the MODEL-AD Center   Howell FAD SfN MODEL-AD poster
Board G13, #467.06 presented 9:00-10:00am

Wednesday, November 7, 1:00 PM – 3:15 PM
Nanosymposium 713: Alzheimer’s Disease and Other Dementias: Abeta: Pathologic Mechanisms
Location: SDCC 33

1:45-2:00 713.04 David Baglietto-Vargas hAb-KI mice: A novel tool for investigating risk factors in sporadic Alzheimer’s cases